Overview

  • Product nameAnti-KRT71 antibody
    See all KRT71 primary antibodies
  • Description
    Mouse monoclonal to KRT71
  • Tested applicationsSuitable for: WB, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 251-333 of Human KRT71 with proprietary tag (NP_258259).

  • Positive control
    • KRT71 transfected 293T cell line.

Properties

Applications

Our Abpromise guarantee covers the use of ab118124 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 57 kDa.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

Target

  • FunctionPlays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
  • Tissue specificityHighly expressed in hair follicles from scalp. Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in the all 3 IRS layers: the cuticle, the Henle and the Huxley layers. Also detected in the pseudopods of specialized Huxley cells, termed Fluegelzellen, along the area of differentiated Henle cells (at protein level).
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Developmental stageIn all 3 IRS layers, expression begins simultaneously in adjacent cells of the lowermost bulb above the germinative cell pool and terminated higher up in the follicle with the asynchronous terminal differentiation of each cell layer (at protein level).
  • Information by UniProt
  • Database links
  • Alternative names
    • CK-71 antibody
    • Cytokeratin-71 antibody
    • hK6irs antibody
    • hK6irs1 antibody
    • K2C71_HUMAN antibody
    • K6IRS1 antibody
    • K71 antibody
    • Keratin 6 irs antibody
    • Keratin antibody
    • keratin, type II cytoskeletal 71 antibody
    • Keratin-71 antibody
    • KRT6IRS antibody
    • KRT6IRS1 antibody
    • KRT71 antibody
    • MGC119390 antibody
    • MGC119391 antibody
    • OTTHUMP00000236990 antibody
    • type II cytoskeletal 71 antibody
    • Type II inner root sheath-specific keratin-K6irs1 antibody
    • Type-II keratin Kb34 antibody
    see all

Anti-KRT71 antibody images

  • Anti-KRT71 antibody (ab118124) at 5 µg/ml + recombinant immunogen at 0.2 µg

    Predicted band size : 57 kDa
  • All lanes : Anti-KRT71 antibody (ab118124) at 5 µg/ml

    Lane 1 : 293T cell line lysate, transfected with KRT71
    Lane 2 : 293T cell line lysate, non-transfected

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 57 kDa
  • Detection limit for recombinant tagged KRT71 is 0.1 ng/ml as a capture antibody.

References for Anti-KRT71 antibody (ab118124)

ab118124 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"