Recombinant
RabMAb

Anti-KRTHB3 antibody [EPR12333] (ab174272)

Overview

  • Product name
    Anti-KRTHB3 antibody [EPR12333]
    See all KRTHB3 primary antibodies
  • Description
    Rabbit monoclonal [EPR12333] to KRTHB3
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment within Human KRTHB3. The exact sequence is proprietary.
    Database link: P78385

  • Positive control
    • Human skin, C6, and NIH 3T3 lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.2
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 49% PBS, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR12333
  • Isotype
    IgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab174272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 54 kDa (predicted molecular weight: 54 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Tissue specificity
      Synthesis begins in the cortex 10-15 cell layers above the apex of the dermal papilla and ends abruptly in the middle of the cortex.
    • Involvement in disease
      Defects in KRT83 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
    • Sequence similarities
      Belongs to the intermediate filament family.
    • Information by UniProt
    • Database links
    • Alternative names
      • Hair keratin K2.10 antibody
      • Hard keratin, type II, 3 antibody
      • HB 3 antibody
      • HB3 antibody
      • hHb3 antibody
      • K2.10 antibody
      • K83 antibody
      • Keratin 83 antibody
      • Keratin antibody
      • Keratin, hair, basic, 3 antibody
      • Keratin-83 antibody
      • Krt83 antibody
      • KRT83_HUMAN antibody
      • KRTHB3 antibody
      • type II cuticular Hb3 antibody
      • Type II hair keratin Hb3 antibody
      • Type-II keratin Kb23 antibody
      see all

    Images

    • All lanes : Anti-KRTHB3 antibody [EPR12333] (ab174272) at 1/1000 dilution

      Lane 1 : Human skin lysate
      Lane 2 : C6 lysate
      Lane 3 : NIH 3T3 lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 54 kDa

    References

    ab174272 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab174272.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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