Overview

  • Product name
    Anti-KSHV ORF8 antibody
  • Description
    Rabbit polyclonal to KSHV ORF8
  • Tested applications
    Suitable for: WBmore details
  • Immunogen

    Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.

  • Positive control
    • TPA-induced BCBL-1 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.05% Sodium azide
    Constituent: PBS
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab36599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 68 kDa.

Target

  • Relevance
    Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
  • Alternative names
    • HHV 8 antibody
    • Human herpesvirus 8 antibody
    • Kaposi's sarcoma herpes virus antibody
    • KSHV antibody
    • ORF8 antibody
    see all

Images

  • All lanes : Anti-KSHV ORF8 antibody (ab36599)

    Lane 1 : Uninduced BCBL-1 cell lysate
    Lane 2 : TPA induced BCBL-1 cell lysate
    Lane 3 : Purified virion

References

This product has been referenced in:
  • Lin X  et al. MicroRNAs and unusual small RNAs discovered in Kaposi's sarcoma-associated herpesvirus virions. J Virol 86:12717-30 (2012). Read more (PubMed: 22973026) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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