• Product nameAnti-Kv beta 1 antibody [S40-17]
    See all Kv beta 1 primary antibodies
  • Description
    Mouse monoclonal [S40-17] to Kv beta 1
  • Tested applicationsSuitable for: ICC/IF, IHC-P, IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Full length protein, corresponding to amino acids 1 - 401 of Rat Kv beta 1 (P63144).

  • Positive control
    • Rat brain lysate


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberS40-17
  • IsotypeIgG2a
  • Research areas


Our Abpromise guarantee covers the use of ab99012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 0.1 - 1 µg/ml. (perox) or 1 - 10 µg/ml (IF).
IHC-P Use a concentration of 0.1 - 1 µg/ml. (perox) or 1 - 10 µg/ml (IF).
IHC-Fr Use a concentration of 0.1 - 1 µg/ml. (perox) or 1 - 10 µg/ml (IF).
WB Use a concentration of 1 µg/ml. Detects a band of approximately 30 - 45 kDa.


  • FunctionAccessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1.
  • Tissue specificityIn brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium.
  • Sequence similaritiesBelongs to the shaker potassium channel beta subunit family.
  • DomainAlteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • hKvb3 antibody
    • hKvBeta3 antibody
    • K(+) channel subunit beta-1 antibody
    • KCAB1_HUMAN antibody
    • KCNA1B antibody
    • KCNAB1 antibody
    • Kv-beta-1 antibody
    • Kvb1.3 antibody
    • Voltage-gated potassium channel beta-1 subunit antibody
    • Voltage-gated potassium channel subunit beta-1 antibody
    see all

Anti-Kv beta 1 antibody [S40-17] images

  • Image from David M et al., J Biol Chem. 2012 Jun 15;287(25):21416-28. Epub 2012 Apr 30.Fig 10.; doi: 10.1074/jbc.M111.328278; June 15, 2012, The Journal of Biological Chemistry, 287, 21416-21428.

References for Anti-Kv beta 1 antibody [S40-17] (ab99012)

This product has been referenced in:
  • David M  et al. Protein Kinase C (PKC) Activity Regulates Functional Effects of Kvß1.3 Subunit on KV1.5 Channels: IDENTIFICATION OF A CARDIAC Kv1.5 CHANNELOSOME. J Biol Chem 287:21416-28 (2012). WB ; Human . Read more (PubMed: 22547057) »

See 1 Publication for this product

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