Overview

  • Product nameAnti-Kv beta 1 antibody [S9-40]
    See all Kv beta 1 primary antibodies
  • Description
    Mouse monoclonal [S9-40] to Kv beta 1
  • SpecificityReacts with Kv beta 1.1. Does not cross-react with Kv beta 1.2, Kv beta 1.3 or Kv beta 2.
  • Tested applicationsSuitable for: WB, ICC, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Pig
  • Immunogen

    Synthetic peptide:

    TEHNLKSPNGEDRLLSKQSST

    , corresponding to N terminal amino acids 7-28 of Rat Kv beta 1 (NP_058999)

  • Positive control
    • Transfected COS cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberS9-40
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98969 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa.
ICC Use a concentration of 0.1 - 1 µg/ml.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.

Target

  • FunctionAccessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. All three isoforms alter the functional properties of Kv1.4 and Kv1.5. Isoform KvB1.2 has no effect on Kv1.1, Kv1.2 or Kv2.1.
  • Tissue specificityIn brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium.
  • Sequence similaritiesBelongs to the shaker potassium channel beta subunit family.
  • DomainAlteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • hKvb3 antibody
    • hKvBeta3 antibody
    • K(+) channel subunit beta-1 antibody
    • KCAB1_HUMAN antibody
    • KCNA1B antibody
    • KCNAB1 antibody
    • Kv-beta-1 antibody
    • Kvb1.3 antibody
    • Voltage-gated potassium channel beta-1 subunit antibody
    • Voltage-gated potassium channel subunit beta-1 antibody
    see all

Anti-Kv beta 1 antibody [S9-40] images

  • Immunohistochemical detection of Kv beta 1 using ab98969 in Mouse brain tissue sections. Granular staining of the cytoplasm of neurons. The rest of the cells are negative.

References for Anti-Kv beta 1 antibody [S9-40] (ab98969)

ab98969 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"