Anti-Kv beta 2 antibody [S17-70] (ab98971)

Overview

  • Product nameAnti-Kv beta 2 antibody [S17-70]
    See all Kv beta 2 primary antibodies
  • Description
    Mouse monoclonal [S17-70] to Kv beta 2
  • Tested applicationsSuitable for: ICC, ICC/IF, WB, IP, IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human, Zebrafish
  • Immunogen

    Fusion protein of full length Rat Kv beta 2

  • Positive control
    • Rat brain lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone numberS17-70
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 1 - 10 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa.
IP Use at an assay dependent concentration.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.

Target

  • RelevanceVoltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence related potassium channel genes: shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog(s). This protein belongs to the potassium channel, voltage gated, shaker related subfamily and is one of the beta subunits, which are auxiliary proteins associating with functional Kv alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • AKR6A5 antibody
    • HKv beta 2 antibody
    • HKvbeta 2 antibody
    • HKvbeta2 antibody
    • HKvbeta2.1 antibody
    • HKvbeta2.2 antibody
    • K(+) channel subunit beta 2 antibody
    • K+ channel beta 2 subunit antibody
    • KCNA 2B antibody
    • KCNA2B antibody
    • KCNAB 2 antibody
    • KCNAB2 antibody
    • KCNK 2 antibody
    • KCNK2 antibody
    • Kv beta2 antibody
    • Kvbeta2 antibody
    • MGC117289 antibody
    • Potassium channel shaker chain beta 2 antibody
    • Potassium voltage gated channel shaker related subfamily antibody
    • Potassium voltage gated channel shaker related subfamily beta member 2 antibody
    • potassium voltage-gated channel, shaker-related subfamily, beta member 1 antibody
    • Voltage gated potassium channel beta 2 subunit antibody
    • Voltage gated potassium channel subunit beta 2 antibody
    see all

References for Anti-Kv beta 2 antibody [S17-70] (ab98971)

ab98971 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The immunogen for this antibody was rat Kv beta 2, which only has one isoform. Please see the link below to the Swiss-Prot entry for more information:

http://www.uniprot.org/uniprot/P62483


I hope this...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"