Overview

  • Product nameAnti-Kv1.6 antibody [S19-36]
    See all Kv1.6 primary antibodies
  • Description
    Mouse monoclonal [S19-36] to Kv1.6
  • Specificityab110120 does not cross react with other Kv1 channels.
  • Tested applicationsSuitable for: WB, IHC-P, IHC-Fr, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow
  • Immunogen

    Synthetic peptide:

    RERRSSYLPTPHRAYAEKR

    , corresponding to C terminal amino acids 507-525 of Rat Kv1.6.

  • Positive control
    • Rat brain lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage bufferpH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: 50% PBS, 50% Glycerol
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesab110120 is PEG Purified.
  • ClonalityMonoclonal
  • Clone numberS19-36
  • IsotypeIgG3
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab110120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 1 - 10 µg/ml.

Target

  • FunctionMediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similaritiesBelongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.6/KCNA6 sub-subfamily.
  • DomainThe N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • HBK 2 antibody
    • HBK2 antibody
    • Human brain potassium channel 2 antibody
    • KCNA 6 antibody
    • Kcna6 antibody
    • KCNA6_HUMAN antibody
    • Potassium voltage gated channel shaker related subfamily member 6 antibody
    • Potassium voltage gated channel subfamily A member 6 antibody
    • Potassium voltage-gated channel subfamily A member 6 antibody
    • Voltage gated potassium channel protein Kv1.6 antibody
    • Voltage gated potassium channel subunit Kv1.6 antibody
    • Voltage-gated potassium channel HBK2 antibody
    • Voltage-gated potassium channel subunit Kv1.6 antibody
    see all

Anti-Kv1.6 antibody [S19-36] images

  • Immunohistochemical detection of Kv1.6 in frozen sections of Mouse brain extract using ab110120.

References for Anti-Kv1.6 antibody [S19-36] (ab110120)

ab110120 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"