Anti-Kv2.2 antibody - N-terminal (ab174238)

Overview

  • Product name
    Anti-Kv2.2 antibody - N-terminal
    See all Kv2.2 primary antibodies
  • Description
    Rabbit polyclonal to Kv2.2 - N-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rabbit, Cow
  • Immunogen

    Synthetic peptide within Human Kv2.2 aa 138-166 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q92953

  • Positive control
    • 293 cell lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab174238 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab174238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 102 kDa.

Target

  • Function
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
  • Sequence similarities
    Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
  • Domain
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • delayed rectifier potassium channel protein antibody
    • KCNB2 antibody
    • KCNB2_HUMAN antibody
    • potassium channel Kv2.2 antibody
    • potassium voltage gated channel subfamily B member 2 antibody
    • Potassium voltage-gated channel subfamily B member 2 antibody
    • Voltage-gated potassium channel subunit Kv2.2 antibody
    see all

Images

  • Anti-Kv2.2 antibody - N-terminal (ab174238) at 1/100 dilution + 293 cell lysate at 35 µg

    Predicted band size : 102 kDa

References

ab174238 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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