Overview

  • Product nameAnti-Kv4.2 antibody
    See all Kv4.2 primary antibodies
  • Description
    Rabbit polyclonal to Kv4.2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a sequence between N terminal amino acids 122-151 of Human Kv4.2 (NP_036413.1).

  • Positive control
    • K562 cell line lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab123688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 71 kDa.

Target

  • FunctionPore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
  • Tissue specificityHighly expressed throughout the brain. Expression is very low or absent in other tissues.
  • Sequence similaritiesBelongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
  • DomainThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Post-translational
    modifications
    Phosphorylated on serine and threonine residues.
  • Cellular localizationCell membrane. Cell projection > dendrite. Detected in dendrites in cultured hippocampal neurons. Association with KCNIP2 probably enhances cell surface expression.
  • Information by UniProt
  • Database links
  • Alternative names
    • KCD2 antibody
    • KCND 2 antibody
    • KCND2 antibody
    • KCND2_HUMAN antibody
    • KIAA1044 antibody
    • MGC119702 antibody
    • MGC119703 antibody
    • Potassium voltage gated channel Shal related subfamily member 2 antibody
    • Potassium voltage-gated channel subfamily D member 2 antibody
    • RK 5 antibody
    • RK5 antibody
    • Voltage gated potassium channel Kv4.2 antibody
    • Voltage gated potassium channel subunit Kv4.2 antibody
    • Voltage sensitive potassium channel antibody
    • Voltage-gated potassium channel subunit Kv4.2 antibody
    see all

Anti-Kv4.2 antibody images

  • Anti-Kv4.2 antibody (ab123688) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 71 kDa

References for Anti-Kv4.2 antibody (ab123688)

ab123688 has not yet been referenced specifically in any publications.

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