Overview

  • Product nameAnti-Kynurenic acid antibody
  • Description
    Rabbit polyclonal to Kynurenic acid
  • SpecificityThis antibody targets conjugated Kynurenic acid, it doesn't recognize free Kynurenic acid.
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Immunogen

    Chemical/ Small Molecule corresponding to Kynurenic acid conjugated to Bovine Serum Albumin (BSA).

Properties

Applications

Our Abpromise guarantee covers the use of ab37105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Target

  • RelevanceKynurenic acid is a product of the normal metabolism of amino acid L-tryptophan. It is formed from L-kynurenine, a reaction catalyzed by the enzyme kynurenine-oxoglutarate transaminase. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important neurophysiologic and neuropathologic processes. As a result, kynurenic acid has been considered for use in therapy in certain neurobiological disorders. High levels of kynurenic acid have been identified in human urine in certain metabolic disorders, such as marked pyridoxine deficiency and deficiency/absence of kynureninase.
  • Alternative names
    • Kinurenic acid antibody
    • Kynuronic acid antibody
    • Quinurenic acid antibody
    • Transtorine antibody

References for Anti-Kynurenic acid antibody (ab37105)

This product has been referenced in:
  • Lee JC  et al. Ischemic preconditioning protects neurons from damage and maintains the immunoreactivity of kynurenic acid in the gerbil hippocampal CA1 region following transient cerebral ischemia. Int J Mol Med 35:1537-44 (2015). IHC ; Gerbil . Read more (PubMed: 25872573) »

See 1 Publication for this product

Product Wall



I am happy to confirm that both antibodies are recognizing t to their target in dependent of the species that sample originates from.

The targets are not proteins or peptides but are chemical compounds (metabolite) that have the sam...

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Thank you for contacting us.

The source of the antibody informed me that the anti-Kynurenic acid antibodies ab37105 and ab111213 have been characterised in IHC using a perfusion mixture that contains 2% of gluteraldehyde in order to complete t...

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Thank you for your patience.

I have heard back regarding ab36926, ab37105 and ab111013:

Each molecule was conjugated via the COOH group to the carrier protein.

I hope this information is helpful to you. Please do not hes...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"