Overview

  • Product name
    L-Kynurenine
  • Description
    Endogenous AhR agonist
  • Biological description
    Endogenous AhR agonist. L-Tryptophan (ab146400) metabolite. Suppresses allogeneic T cell proliferation. Centrally active.

Properties

  • Chemical name
    (2S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
  • Molecular weight
    208.21
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C10H12N2O3
  • CAS Number
    2922-83-0
  • PubChem identifier
    161166
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 10 mM and in DMSO to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    C1=CC=C(C(=C1)C(=O)C[C@@H](C(=O)O)N)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Blanco Ayala T  et al. Alternative kynurenic acid synthesis routes studied in the rat cerebellum. Front Cell Neurosci 9:178 (2015). Read more (PubMed: 26041992) »
  • Varga D  et al. Systemic L-Kynurenine sulfate administration disrupts object recognition memory, alters open field behavior and decreases c-Fos immunopositivity in C57Bl/6 mice. Front Behav Neurosci 9:157 (2015). Read more (PubMed: 26136670) »
  • He W  et al. A small-molecule screen identifies L-kynurenine as a competitive inhibitor of TAA1/TAR activity in ethylene-directed auxin biosynthesis and root growth in Arabidopsis. Plant Cell 23:3944-60 (2011). Read more (PubMed: 22108404) »

See 0 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab146162.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up