Overview

  • Product name
  • Description
    Rabbit polyclonal to L2
  • Host species
    Rabbit
  • Specificity
    At least two isoforms of L2 are known to exist; ab189424 will detect only the longer isoform.
  • Tested applications
    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human L2 (internal sequence). 16 amino acids. NP_851853.1.
    Database link: Q8NC56

  • Positive control
    • Human skin tissue; 3T3 cells; 293 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab189424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 57 kDa.
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function
    Involved in nuclear structure organization.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Contains 1 LEM domain.
  • Cellular localization
    Nucleus inner membrane. Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.
  • Information by UniProt
  • Database links
  • Alternative names
    • BC026588 antibody
    • dJ482C21.1 antibody
    • hLEM2 antibody
    • Hypothetical protein FLJ90478 antibody
    • Hypothetical protein LEMD2 antibody
    • LEM domain containing 2 antibody
    • LEM domain-containing protein 2 antibody
    • Lem2 antibody
    • Lemd2 antibody
    • LEMD2_HUMAN antibody
    • MGC112806 antibody
    • MGC37253 antibody
    • NET25 antibody
    • OTTHUMP00000016218 antibody
    • OTTHUMP00000039610 2 antibody
    see all

Images

  • Lane 1 : Anti-L2 antibody (ab189424) at 1 µg/ml
    Lane 2 : Anti-L2 antibody (ab189424) at 2 µg/ml

    All lanes : 293 cell lysate

    Predicted band size: 57 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling L2 with ab189424 at 5 µg/ml.

  • Immunofluorescenct analysis of 3T3 cells labeling L2 with ab189424 at 20 µg/ml.

  • Immunocytochemical analysis of 3T3 cells labeling L2 with ab189424 at 2.5 µg/ml.

References

ab189424 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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