Overview

  • Product nameAnti-L3MBTL2 antibody
    See all L3MBTL2 primary antibodies
  • Description
    Rabbit polyclonal to L3MBTL2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog
  • Immunogen

    Synthetic peptide: LKAKEATKKK KKQFGKKRKR IPPTKTRPLR QGSKKPLLED DPQGARKISS , corresponding to amino acids 613-662 of Human L3MBTL2

  • Positive control
    • HEK 293T nuclear cell lysate and human kidney tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab51286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.625 µg/ml. Detects a band of approximately 69 kDa (predicted molecular weight: 79 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

Target

  • FunctionPutative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
  • Sequence similaritiesContains 1 FCS-type zinc finger.
    Contains 4 MBT repeats.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3bt like 2 protein antibody
    • 3bt like protein antibody
    • DKFZP761I141 antibody
    • H-l(3)mbt-like protein 2 antibody
    • H-l(3)mbt-like protein antibody
    • Hl antibody
    • Hl(3)mbt like protein antibody
    • Hl(3)mbtl antibody
    • L antibody
    • l(3)mbt like 2 (Drosophila) antibody
    • l(3)mbt like 2 antibody
    • L(3)mbt-like 2 protein antibody
    • L(3)mbt-like protein 2 antibody
    • L3MBTL2 antibody
    • Lethal antibody
    • Lethal(3)malignant brain tumor-like 2 protein antibody
    • Lethal(3)malignant brain tumor-like protein 2 antibody
    • LMBL2_HUMAN antibody
    see all

Anti-L3MBTL2 antibody images

  • Anti-L3MBTL2 antibody (ab51286) at 0.625 µg/ml + 10 µg of transfected 293T cell lysate

    Secondary
    HRP conjugated anti-Rabbit IgG

    Predicted band size : 79 kDa
  • ab51286 (8µg/ml) staining L3MBTL2 in epithelial cells of renal tubule (arrows) of human kidney Parafin embedded tissue samples by, Immunohistochemistry.

References for Anti-L3MBTL2 antibody (ab51286)

ab51286 has not yet been referenced specifically in any publications.

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