Overview

  • Product nameAnti-L3MBTL2 antibody
    See all L3MBTL2 primary antibodies
  • Description
    Rabbit polyclonal to L3MBTL2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region of human L3MBTL2 (NP_001003689)

  • Positive control
    • HeLa cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab80489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 69 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/312500.

Target

  • FunctionPutative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
  • Sequence similaritiesContains 1 FCS-type zinc finger.
    Contains 4 MBT repeats.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3bt like 2 protein antibody
    • 3bt like protein antibody
    • DKFZP761I141 antibody
    • H-l(3)mbt-like protein 2 antibody
    • H-l(3)mbt-like protein antibody
    • Hl antibody
    • Hl(3)mbt like protein antibody
    • Hl(3)mbtl antibody
    • L antibody
    • l(3)mbt like 2 (Drosophila) antibody
    • l(3)mbt like 2 antibody
    • L(3)mbt-like 2 protein antibody
    • L(3)mbt-like protein 2 antibody
    • L3MBTL2 antibody
    • Lethal antibody
    • Lethal(3)malignant brain tumor-like 2 protein antibody
    • Lethal(3)malignant brain tumor-like protein 2 antibody
    • LMBL2_HUMAN antibody
    see all

Anti-L3MBTL2 antibody images

  • Anti-L3MBTL2 antibody (ab80489) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 69 kDa
    Observed band size : 69 kDa
    Additional bands at : 27 kDa,40 kDa. We are unsure as to the identity of these extra bands.

References for Anti-L3MBTL2 antibody (ab80489)

ab80489 has not yet been referenced specifically in any publications.

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