Overview

  • Product name
  • Description
    Rabbit polyclonal to L3MBTL3
  • Tested applications
    Suitable for: IHC-P, IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Cow, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 550-600 of Human L3MBTL3 (NP_115814.1)

  • Positive control
    • HeLa cells

Properties

Applications

Our Abpromise guarantee covers the use of ab99928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells.
    • Sequence similarities
      Contains 3 MBT repeats.
      Contains 1 SAM (sterile alpha motif) domain.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • L3MBTL3 antibody
      • H-l(3)mbt-like protein 3 antibody
      • Hl(3)mbt like protein antibody
      • KIAA1798 antibody
      • l(3)mbt like 3 (Drosophila) antibody
      • l(3)mbt like 3 antibody
      • L(3)mbt like 3 protein antibody
      • L(3)mbt-like protein 3 antibody
      • L3mbtl3 antibody
      • Lethal(3)malignant brain tumor like 3 protein antibody
      • Lethal(3)malignant brain tumor-like protein 3 antibody
      • LMBL3_HUMAN antibody
      • MBT-1 antibody
      • MBT1 antibody
      • RP11-73O6.1 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung carcinoma tissue labelling L3MBTL3 with ab99928 at 1/1000 (1µg/ml). Detection: Peroxidase Substrate.
    • Immunoprecipitation analysis of HeLa whole cell lysate (1mg/IP; 20% of IP loaded/lane) using ab99928 at 3µg/mg lysate. A rabbit anti-human L3MBTL3 was used for the western blot at 1µg/ml.

      Left Lane - ab99928 IP, Right Lane - control IgG.

    References

    ab99928 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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