Anti-Lactoferrin antibody [EPR4338] (ab109000)

Overview

  • Product nameAnti-Lactoferrin antibody [EPR4338]
    See all Lactoferrin primary antibodies
  • Description
    Rabbit monoclonal [EPR4338] to Lactoferrin
  • Tested applicationsSuitable for: WB, IP, IHC-Pmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Lactoferrin.

  • Positive control
    • Human peripheral blood mononuclear cell (PBMC) lysate; Human breast and Human tonsil tissues.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab109000 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 85 kDa (predicted molecular weight: 78 kDa).
IP 1/10 - 1/100.
IHC-P 1/100 - 1/250. Antigen retrieval is recommended.
  • Application notesIs unsuitable for Flow Cyt or ICC.
  • Target

    • FunctionTransferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
      Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.
      Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.
      The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
    • Sequence similaritiesBelongs to the transferrin family.
      Contains 2 transferrin-like domains.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • GIG12 antibody
      • Growth inhibiting protein 12 antibody
      • HLF2 antibody
      • Kaliocin 1 antibody
      • Lactoferrin antibody
      • Lactoferroxin-C antibody
      • Lactotransferrin antibody
      • LF antibody
      • LTF antibody
      • Neutrophil lactoferrin antibody
      • Talalactoferrin antibody
      • TRFL_HUMAN antibody
      see all

    Anti-Lactoferrin antibody [EPR4338] images

    • Anti-Lactoferrin antibody [EPR4338] (ab109000) at 1/1000 dilution + Human peripheral blood mononuclear cell (PBMC) lysate at 10 µg

      Predicted band size : 78 kDa
    • ab109000 at 1/100 dilution staining Lactoferrin in Human breast by Immunohistochemistry, Paraffin-embedded tissue.
    • ab109000 at 1/100 dilution staining Lactoferrin in Human tonsil by Immunohistochemistry, Paraffin-embedded tissue.

    References for Anti-Lactoferrin antibody [EPR4338] (ab109000)

    ab109000 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"