Overview

  • Product nameAnti-Laeverin antibody
    See all Laeverin primary antibodies
  • Description
    Mouse polyclonal to Laeverin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human Laeverin protein (AAH45809).

  • Positive control
    • Laeverin transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab72692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Predicted molecular weight (for isoform 4): 22 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMetalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.
    • Tissue specificitySpecifically expressed in placenta and not in other tissues. Mainly found at the cell surface region of the extravillous trophoblasts. Detected on extravillous trophoblasts in the outer layer of the chorion laeve in the fetal membrane Not detected on either fetal amnionic epithelial cells or maternal decidual cells. Also detected in the migrating extravillous trophoblasts in the maternal decidual tissues (at protein level).
    • Sequence similaritiesBelongs to the peptidase M1 family.
    • Post-translational
      modifications
      N-glycosylated.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Aminopeptidase Q antibody
      • AMPQ_HUMAN antibody
      • AP-Q antibody
      • APQ antibody
      • Aqpep antibody
      • CHL2 antigen antibody
      • FLJ90650 antibody
      • Laeverin antibody
      • LVRN antibody
      • MGC125378 antibody
      • MGC125379 antibody
      • RGD1562779 antibody
      see all

    Anti-Laeverin antibody images

    • All lanes : Anti-Laeverin antibody (ab72692) at 1/500 dilution

      Lane 1 : Laeverin transfected 293T lysate
      Lane 2 : Non transfected 293T lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

      Predicted band size : 22 kDa
      Observed band size : 20 kDa (why is the actual band size different from the predicted?)

    References for Anti-Laeverin antibody (ab72692)

    ab72692 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab72692.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"