Anti-Laminin alpha 5 antibody [4B12] (ab77175)

Overview

  • Product nameAnti-Laminin alpha 5 antibody [4B12]
    See all Laminin alpha 5 primary antibodies
  • Description
    Mouse monoclonal [4B12] to Laminin alpha 5
  • Tested applicationsSuitable for: ELISA, IHC-P, IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Laminin purified from human placenta.

  • Positive control
    • Human embryonic lung (alveolar epithelium). Human kidney.

Properties

Applications

Our Abpromise guarantee covers the use of ab77175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
IP 1/20.
  • Application notesIs unsuitable for WB.
  • Target

    • RelevanceLaminins are a family of heterotrimeric extracellular glycoproteins consisting of alpha, beta, and gamma chains. Laminins are thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin alpha 5 (LAMA5) belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Laminin alpha 5 is the alpha chain in the Laminin 15 complex which is a heterotrimer composed of alpha 5/beta 2/gamma 3 which are bound to each other by disulfide bonds into a cross shaped molecule comprising one long and three short arms with globules at each end.
    • Cellular localizationSecreted; basement membrane.
    • Database links
    • Alternative names
      • KIAA0533 antibody
      • KIAA1907 antibody
      • LAMA5 antibody
      • Laminin alpha 5 chain antibody
      • Laminin subunit alpha 5 antibody
      • Laminin subunit alpha-5 antibody
      • Laminin, alpha 5 antibody
      • Laminin-10 subunit alpha antibody
      • Laminin-11 subunit alpha antibody
      • Laminin-15 subunit alpha antibody
      • RP11-157P1.6 antibody
      see all

    Anti-Laminin alpha 5 antibody [4B12] images

    • Immunofluorescence of (A) Human embryonic lung alveolae epithelium and (B) Human kidney labelling Lamin alpha 5 with ab77175.

    References for Anti-Laminin alpha 5 antibody [4B12] (ab77175)

    ab77175 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"