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Products:Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina
Overview
Product name
Anti-Laminin alpha 5 antibody
See all Laminin alpha 5 products (4) ...
Description
Mouse monoclonal to Laminin alpha 5
Tested applications
Cross reactivity
Reacts with
Recombinant Fragment
Predicted to work with
Human
Immunogen
Recombinant fragment: MGVSLRDKKV HWVYQLGEAG PAVLSIDEDI GEQFAAVSLD RTLQFGHMSV TVERQMIQET KGDTVAPGAE GLLNLRPDDF VFYVGGYPST FTPPPLLRFP , corresponding to amino acids 1-100 of Human Laminin alpha 5
MGVSLRDKKV HWVYQLGEAG PAVLSIDEDI GEQFAAVSLD RTLQFGHMSV TVERQMIQET KGDTVAPGAE GLLNLRPDDF VFYVGGYPST FTPPPLLRFP
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina
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Western blot - Laminin alpha 5 antibody (ab55413)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55413 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Laminins are a family of heterotrimeric extracellular glycoproteins consisting of alpha, beta, and gamma chains. Laminins are thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin alpha 5 (LAMA5) belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Laminin alpha 5 is the alpha chain in the Laminin 15 complex which is a heterotrimer composed of alpha 5/beta 2/gamma 3 which are bound to each other by disulfide bonds into a cross shaped molecule comprising one long and three short arms with globules at each end.
Cellular localization
Secreted; basement membrane.
Alternative names
- LAMA5 antibody
- Laminin alpha 5 chain antibody
- Laminin subunit alpha 5 antibody
see all
Database links
- Entrez Gene: 3911 Human
- Omim: 601033 Human
- SwissProt: O15230 Human
Anti-Laminin alpha 5 antibody images:
Western blot - Laminin alpha 5 antibody (ab55413)
Western blot against tagged recombinant protein immunogen using ab55413 Laminin alpha 5 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
References for Anti-Laminin alpha 5 antibody (ab55413)
ab55413 has not yet been referenced specifically in any publications.
Publishing research using ab55413? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"