Recombinant
RabMAb

Anti-Laminin beta 1 antibody [EPR3190(2)] (ab109293)

Overview

  • Product name
    Anti-Laminin beta 1 antibody [EPR3190(2)]
    See all Laminin beta 1 primary antibodies
  • Description
    Rabbit monoclonal [EPR3190(2)] to Laminin beta 1
  • Tested applications
    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human Laminin beta 1.

  • Positive control
    • Human fetal kidney and A431 lysates, A431 cells
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab109293 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 220 kDa (predicted molecular weight: 198 kDa).
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
    • Sequence similarities
      Contains 13 laminin EGF-like domains.
      Contains 1 laminin IV type B domain.
      Contains 1 laminin N-terminal domain.
    • Domain
      The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
      Domains VI and IV are globular.
    • Cellular localization
      Secreted > extracellular space > extracellular matrix > basement membrane. Major component.
    • Information by UniProt
    • Database links
    • Alternative names
      • CLM antibody
      • Cutis laxa with marfanoid phenotype antibody
      • LAM B1 antibody
      • LAMB 1 antibody
      • LAMB1 antibody
      • LAMB1_HUMAN antibody
      • Laminin B1 antibody
      • Laminin B1 chain antibody
      • Laminin beta 1 chain antibody
      • Laminin beta 1 chain precursor antibody
      • Laminin beta1 antibody
      • Laminin subunit beta 1 antibody
      • Laminin subunit beta-1 antibody
      • Laminin-1 subunit beta antibody
      • Laminin-10 subunit beta antibody
      • Laminin-12 subunit beta antibody
      • Laminin-2 subunit beta antibody
      • Laminin-6 subunit beta antibody
      • Laminin-8 subunit beta antibody
      • LIS5 antibody
      • MGC142015 antibody
      see all

    Images

    • All lanes : Anti-Laminin beta 1 antibody [EPR3190(2)] (ab109293) at 1/1000 dilution

      Lane 1 : Human fetal kidney lysate
      Lane 2 : A431 lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 198 kDa
    • Flow cytometric analysis of permeabilized A431 cells using ab109293 (red) at a diluiton of 1/100 or a rabbit IgG (negative) (green).

    References

    ab109293 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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