Overview

  • Product name
    Anti-Laminin gamma 1 antibody
    See all Laminin gamma 1 primary antibodies
  • Description
    Rabbit polyclonal to Laminin gamma 1
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Drosophila melanogaster
  • Immunogen

    Full length native protein (purified) (Fruit fly (Drosophila melanogaster))

Properties

Applications

Our Abpromise guarantee covers the use of ab47651 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 182 kDa.
ICC/IF 1/500.

Target

  • Function
    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
  • Tissue specificity
    Found in the basement membranes (major component).
  • Sequence similarities
    Contains 11 laminin EGF-like domains.
    Contains 1 laminin IV type A domain.
    Contains 1 laminin N-terminal domain.
  • Domain
    The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
    Domains VI and IV are globular.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix > basement membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • LAMB2 antibody
      • lamc1 antibody
      • LAMC1_HUMAN antibody
      • Laminin B2 chain antibody
      • Laminin subunit gamma-1 antibody
      • Laminin, gamma 1 (formerly LAMB2) antibody
      • Laminin-1 subunit gamma antibody
      • Laminin-10 subunit gamma antibody
      • Laminin-11 subunit gamma antibody
      • Laminin-2 subunit gamma antibody
      • Laminin-3 subunit gamma antibody
      • Laminin-4 subunit gamma antibody
      • Laminin-6 subunit gamma antibody
      • Laminin-7 subunit gamma antibody
      • Laminin-8 subunit gamma antibody
      • Laminin-9 subunit gamma antibody
      • MGC87297 antibody
      • S-LAM gamma antibody
      • S-laminin subunit gamma antibody
      see all

    References

    This product has been referenced in:
    • Bangi E  et al. Functional exploration of colorectal cancer genomes using Drosophila. Nat Commun 7:13615 (2016). IHC ; Drosophila melanogaster . Read more (PubMed: 27897178) »
    • Schleede J & Blair SS The Gyc76C Receptor Guanylyl Cyclase and the Foraging cGMP-Dependent Kinase Regulate Extracellular Matrix Organization and BMP Signaling in the Developing Wing of Drosophila melanogaster. PLoS Genet 11:e1005576 (2015). IHC ; Drosophila melanogaster . Read more (PubMed: 26440503) »

    See all 8 Publications for this product

    Customer reviews and Q&As

    Thank you for your interest.
    Generally, we do not test our antibodies in insect species - mainly in mammalian system (human, mouse and rat).
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