Anti-CD208 antibody (ab111090)
Key features and details
- Rabbit polyclonal to CD208
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CD208 antibody
See all CD208 primary antibodies -
Description
Rabbit polyclonal to CD208 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human CD208 (internal sequence).
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Positive control
- Human lung carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine), 49.1% PBS
PBS (without Mg2+ and Ca2+) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab111090 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab111090 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells. -
Tissue specificity
Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues. -
Sequence similarities
Belongs to the LAMP family. -
Cellular localization
Lysosome membrane. - Information by UniProt
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Database links
- Entrez Gene: 27074 Human
- Omim: 605883 Human
- SwissProt: Q9UQV4 Human
- Unigene: 518448 Human
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Alternative names
- CD208 antibody
- CD208 antigen antibody
- DC LAMP antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (9)
ab111090 has been referenced in 9 publications.
- Zhang Z et al. Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients. Clin Transl Med 12:e1072 (2022). PubMed: 36305631
- Santucci-Pereira J et al. Genomic signature of parity in the breast of premenopausal women. Breast Cancer Res 21:46 (2019). PubMed: 30922380
- Yang C et al. Long noncoding RNA HAGLR acts as a microRNA-143-5p sponge to regulate epithelial-mesenchymal transition and metastatic potential in esophageal cancer by regulating LAMP3. FASEB J 33:10490-10504 (2019). PubMed: 31311326
- Dang Q et al. LAMP1 Overexpression Predicts for Poor Prognosis in Diffuse Large B-cell Lymphoma. Clin Lymphoma Myeloma Leuk 18:749-754 (2018). PubMed: 30082222
- Wang D et al. LAMP3 expression correlated with poor clinical outcome in human ovarian cancer. Tumour Biol 39:1010428317695014 (2017). PubMed: 28349821
- Lu J et al. Clinical Significance and Prognostic Value of the Expression of LAMP3 in Oral Squamous Cell Carcinoma. Dis Markers 2017:1218254 (2017). IHC-P ; Human . PubMed: 28607528
- Liao X et al. High Expression of LAMP3 Is a Novel Biomarker of Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma. Int J Mol Sci 16:17655-67 (2015). PubMed: 26263981
- Qiu X et al. LAMP3 and TP53 overexpression predicts poor outcome in laryngeal squamous cell carcinoma. Int J Clin Exp Pathol 8:5519-27 (2015). PubMed: 26191259
- Sun R et al. Prognostic value of LAMP3 and TP53 overexpression in benign and malignant gastrointestinal tissues. Oncotarget 5:12398-409 (2014). IHC . PubMed: 25362357