Overview

  • Product name
  • Description
    Rabbit polyclonal to LAMP3
  • Specificity
    Detects endogenous levels of total LAMP3 protein.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from an internal sequence of Human LAMP3.

  • Positive control
    • Human lung carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab111090 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells.
  • Tissue specificity
    Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues.
  • Sequence similarities
    Belongs to the LAMP family.
  • Cellular localization
    Lysosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD208 antibody
    • CD208 antigen antibody
    • DC LAMP antibody
    • DC lysosome associated membrane glycoprotein antibody
    • DC-lysosome-associated membrane glycoprotein antibody
    • DCLAMP antibody
    • LAMP antibody
    • LAMP 3 antibody
    • LAMP-3 antibody
    • Lamp3 antibody
    • LAMP3_HUMAN antibody
    • Lysosomal associated membrane protein 3 antibody
    • Lysosomal-associated membrane protein 3 antibody
    • Lysosome-associated membrane glycoprotein 3 antibody
    • Protein TSC403 antibody
    • TSC403 antibody
    see all

Images

  • ab111090 at 1/50 dilution staining LAMP3 in paraffin-embedded Human Lung carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

References

This product has been referenced in:
  • Lu J  et al. Clinical Significance and Prognostic Value of the Expression of LAMP3 in Oral Squamous Cell Carcinoma. Dis Markers 2017:1218254 (2017). IHC-P ; Human . Read more (PubMed: 28607528) »
  • Liao X  et al. High Expression of LAMP3 Is a Novel Biomarker of Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma. Int J Mol Sci 16:17655-67 (2015). Read more (PubMed: 26263981) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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