Overview

  • Product name
  • Description
    Rabbit polyclonal to LANPL
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to amino acids close to the C terminus of Human LANPL.

  • Positive control
    • Human Brain Cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115448 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 31 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis process by modulating PP2A activity.
  • Tissue specificity
    Expressed in peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney.
  • Sequence similarities
    Belongs to the ANP32 family.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • Post-translational
    modifications
    Phosphorylated. The phosphorylation is nuclear localization signal (NLS)-dependent.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Acidic (leucine rich) nuclear phosphoprotein 32 family member E antibody
    • Acidic leucine-rich nuclear phosphoprotein 32 family member E antibody
    • AN32E_HUMAN antibody
    • anp32e antibody
    • Cerebellar postnatal development protein 1 antibody
    • LANP like protein antibody
    • LANP-L antibody
    • LANP-like protein antibody
    • LANPL antibody
    • Leucine rich acidic nuclear protein like antibody
    • MGC5350 antibody
    see all

Images

  • ab115448, at 2.5ug/ml, staining LANPL in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115448 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab115448.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up