Anti-LARP7 antibody - C-terminal (ab171514)

Overview

  • Product name
    Anti-LARP7 antibody - C-terminal
    See all LARP7 primary antibodies
  • Description
    Rabbit polyclonal to LARP7 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LARP7 aa 526-556 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q4G0J3

  • Positive control
    • WiDr cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab171514 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 66 kDa.

Target

  • Function
    Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
  • Sequence similarities
    Contains 1 HTH La-type RNA-binding domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus > nucleoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp564K112 antibody
    • HDCMA18P antibody
    • La related protein 7 antibody
    • La ribonucleoprotein domain family member 7 antibody
    • La ribonucleoprotein domain family member 7 antibody
    • La-related protein 7 antibody
    • LARP 7 antibody
    • larp7 antibody
    • LARP7_HUMAN antibody
    • MGC104360 antibody
    • P TEFb interaction protein for 7SK stability antibody
    • P-TEFb-interaction protein for 7SK stability antibody
    • PIP7S antibody
    see all

Images

  • Anti-LARP7 antibody - C-terminal (ab171514) at 1/100 dilution + WiDr cell lysate at 35 µg

    Predicted band size: 66 kDa

References

ab171514 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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