Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab65944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 29 kDa).

    Peptide ELISA: antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
    • Sequence similarities
      Contains 1 LIM zinc-binding domain.
      Contains 2 nebulin repeats.
      Contains 1 SH3 domain.
    • Cellular localization
      Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. Associated with the F-actin rich cortical cytoskeleton.
    • Information by UniProt
    • Database links
    • Alternative names
      • LASP 1 antibody
      • LASP-1 antibody
      • LASP1 antibody
      • LASP1_HUMAN antibody
      • LIM and SH3 domain protein 1 antibody
      • LIM and SH3 protein 1 antibody
      • Metastatic lymph node gene 50 protein antibody
      • MLN 50 antibody
      • MLN50 antibody
      • OTTHUMP00000164238 antibody
      • OTTHUMP00000164239 antibody
      see all

    Images

    References

    ab65944 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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