Overview

  • Product name
  • Description
    Rabbit polyclonal to LASS4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    A region within synthetic peptide: PIRRKIKPNP VLEKYFLRMK QCPEETQMVL LASQCGLTLR QTQRWFRRRR, corresponding to N terminal amino acids 73-122 of Human LASS4

  • Positive control
    • NIH3T3 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab66512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.
  • Sequence similarities
    Contains 1 homeobox DNA-binding domain.
    Contains 1 TLC (TRAM/LAG1/CLN8) domain.
  • Cellular localization
    Nucleus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ceramide synthase 4 antibody
    • CerS4 antibody
    • FLJ12089 antibody
    • LAG1 homolog ceramide synthase 4 antibody
    • LAG1 longevity assurance homolog 4 antibody
    • LAG1, S. cerevisiae, homolog of, 4 antibody
    • LASS 4 antibody
    • LASS4 antibody
    • LASS4 LAG1 homolog ceramide synthase 4 antibody
    • LASS4_HUMAN antibody
    • TRAM homolog 1 antibody
    • Trh 1 antibody
    • Trh1 antibody
    see all

Images

  • Anti-LASS4 antibody (ab66512) at 2.5 µg/ml + NIH3T3 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 46 kDa
    Observed band size : 46 kDa

References

ab66512 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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