Overview

  • Product nameAnti-LAT3 antibody
  • Description
    Rabbit polyclonal to LAT3
  • SpecificityThis antibody detects endogenous levels of total LAT3 protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthesized peptide derived from the internal region of human LAT3.

  • Positive control
    • Extracts from Jurkat and A549 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab70177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 61 kDa.
ELISA 1/20000.

Target

  • FunctionSodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.
  • Tissue specificityIn adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.
  • Sequence similaritiesBelongs to the SLC43A transporter (TC 2.A.1.44) family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • L type amino acid transporter 3 antibody
    • L-type amino acid transporter 3 antibody
    • Large neutral amino acids transporter small subunit 3 antibody
    • LAT3_HUMAN antibody
    • PB39 antibody
    • POV1 antibody
    • Prostate cancer overexpressed gene 1 protein antibody
    • R00504 antibody
    • SLC43A1 antibody
    • Solute carrier family 43 member 1 antibody
    see all

Anti-LAT3 antibody images

  • All lanes : Anti-LAT3 antibody (ab70177) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from A549 cells
    Lane 3 : Extracts from Jurkat cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 61 kDa
    Observed band size : 61 kDa
    Additional bands at : 117 kDa,54 kDa,80 kDa. We are unsure as to the identity of these extra bands.

References for Anti-LAT3 antibody (ab70177)

ab70177 has not yet been referenced specifically in any publications.

Product Wall

As shown on the datasheet http://www.abcam.com/ab70177,this anti-LAT3 has been tested in Western Blot andELISA. It hasnot been tested in other applications yet.

Therefore, I can offer a discount off a future purchase if you buy ab70177 now, t...

Read More

Vielen Dank für Ihre Anfrage.


Gerne bin ich Ihnen bei der Wahl eines passenden Antikörpers behilflich. Für welche Spezies suchen Sie den den Antikörper?

Ich freue mich auf Ihre Antwort.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"