Overview

  • Product nameAnti-LBP antibody
    See all LBP primary antibodies
  • Description
    Rabbit polyclonal to LBP
  • Tested applicationsSuitable for: ELISA, Flow Cyt, IP, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Affinity purified recombinant LBP (Human)

  • General notes


    ab25094 shows small inhibition of LPS binding to human CD14.

Properties

Applications

Our Abpromise guarantee covers the use of ab25094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/100 - 1/1000.

Binding titer for human LBP: 1/3000.

Flow Cyt Use at an assay dependent concentration. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 53 kDa.

Target

  • FunctionBinds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
  • Sequence similaritiesBelongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • BPI fold containing family D, member 2 antibody
    • Bpifd2 antibody
    • LBP antibody
    • LBP_HUMAN antibody
    • LBP1 antibody
    • Lipopolysaccharide binding protein antibody
    • Lipopolysaccharide-binding protein antibody
    • LPS binding protein antibody
    • Ly88 antibody
    • MGC22233 antibody
    • OTTHUMP00000030965 antibody
    • RP23-407H16.4 antibody
    see all

References for Anti-LBP antibody (ab25094)

This product has been referenced in:
  • Haziak K  et al. Effects of central injection of anti-LPS antibody and blockade of TLR4 on GnRH/LH secretion during immunological stress in anestrous ewes. Mediators Inflamm 2014:867170 (2014). Sheep . Read more (PubMed: 24719525) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. ab25094 and ab96748 were both raised against recombinant human LBP (full length and region 166-437 respectively). Unfortunately, comparing the human sequence to that of rat yielded only 68% homology. We would theref...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"