Overview

  • Product nameAnti-LCMT1 antibody [4A4]
    See all LCMT1 primary antibodies
  • Description
    Mouse monoclonal [4A4] to LCMT1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Full length mouse LCMT1 with 6His tag

  • Positive control
    • Rat whole brain preparation.

Properties

Applications

Our Abpromise guarantee covers the use of ab77754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa).

Target

  • FunctionMethylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
  • Sequence similaritiesBelongs to the methyltransferase superfamily. LCMT family.
  • Information by UniProt
  • Database links
  • Alternative names
    • [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1 antibody
    • CGI 68 antibody
    • LCMT antibody
    • LCMT1 antibody
    • LCMT1_HUMAN antibody
    • Leucine carboxyl methyltransferase 1 antibody
    • PPMT1 antibody
    • Protein leucine O methyltransferase antibody
    • protein phosphatase methyltransferase 1 antibody
    • Protein-leucine O-methyltransferase antibody
    see all

Anti-LCMT1 antibody [4A4] images

  • Anti-LCMT1 antibody [4A4] (ab77754) at 2 µg/ml + rat whole brain preparation

    Secondary
    Goat anti-mouse HRP conjugate

    Predicted band size : 38 kDa
    Observed band size : 38 kDa
    Additional bands at : 36 kDa. We are unsure as to the identity of these extra bands.

References for Anti-LCMT1 antibody [4A4] (ab77754)

This product has been referenced in:
  • MacKay KB  et al. Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling. PLoS One 8:e65967 (2013). WB ; Mouse . Read more (PubMed: 23840384) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"