Overview

  • Product name
  • Description
    Rabbit polyclonal to LD78 beta
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Horse, Pig
  • Immunogen

    Recombinant full length protein corresponding to Pig LD78 beta aa 8-75.
    Sequence:

    APLGADTPTA CCFSYTSRQL PRKFVADYFE TSSQCSKPGV IFQTKKGREV CANPEDAWVQ EYISDLELNA


    Database link: 494459

  • General notes

    Cross-reactivity determined in ELISA.

Properties

Applications

Our Abpromise guarantee covers the use of ab193959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml.

Target

  • Function
    Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 464.2 antibody
    • C C motif chemokine 3 like 1 antibody
    • CCL3L1 antibody
    • CCL3L3 antibody
    • Chemokine (C C motif) ligand 3 like 1 antibody
    • Chemokine (C C motif) ligand 3 like 3 antibody
    • Chemokine (C C motif) ligand 3 like, centromeric antibody
    • chemokine (CC motif) ligand 3 like 1 antibody
    • CL3L1_HUMAN antibody
    • D17S1718 antibody
    • G0/G1 switch regulatory protein 19-2 antibody
    • G0S19-2 antibody
    • LD78 antibody
    • LD78 beta(1-70) antibody
    • LD78-beta(1-70) antibody
    • LD78-beta(5-70) antibody
    • LD78BETA antibody
    • MGC104178 antibody
    • MGC12815 antibody
    • MGC182017 antibody
    • MIP1AP antibody
    • PAT 464.2 antibody
    • SCYA3L antibody
    • SCYA3L1 antibody
    • Small inducible cytokine A3 like 1 precursor antibody
    • Small-inducible cytokine A3-like 1 antibody
    • Tonsillar lymphocyte LD78 beta antibody
    • Tonsillar lymphocyte LD78 beta protein antibody
    see all

References

ab193959 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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