Overview

  • Product name
    Anti-LD78 beta antibody
    See all LD78 beta primary antibodies
  • Description
    Rabbit polyclonal to LD78 beta
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Horse, Pig
  • Immunogen

    Recombinant full length protein corresponding to Pig LD78 beta aa 8-75.
    Sequence:

    APLGADTPTA CCFSYTSRQL PRKFVADYFE TSSQCSKPGV IFQTKKGREV CANPEDAWVQ EYISDLELNA


    Database link: 494459

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • General notes

    Cross-reactivity determined in ELISA.

Properties

Applications

Our Abpromise guarantee covers the use of ab193959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml.

Target

  • Function
    Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
    • Alternative names
      • 464.2 antibody
      • C C motif chemokine 3 like 1 antibody
      • CCL3L1 antibody
      • CCL3L3 antibody
      • Chemokine (C C motif) ligand 3 like 1 antibody
      • Chemokine (C C motif) ligand 3 like 3 antibody
      • Chemokine (C C motif) ligand 3 like, centromeric antibody
      • chemokine (CC motif) ligand 3 like 1 antibody
      • CL3L1_HUMAN antibody
      • D17S1718 antibody
      • G0/G1 switch regulatory protein 19-2 antibody
      • G0S19-2 antibody
      • LD78 antibody
      • LD78 beta(1-70) antibody
      • LD78-beta(1-70) antibody
      • LD78-beta(5-70) antibody
      • LD78BETA antibody
      • MGC104178 antibody
      • MGC12815 antibody
      • MGC182017 antibody
      • MIP1AP antibody
      • PAT 464.2 antibody
      • SCYA3L antibody
      • SCYA3L1 antibody
      • Small inducible cytokine A3 like 1 precursor antibody
      • Small-inducible cytokine A3-like 1 antibody
      • Tonsillar lymphocyte LD78 beta antibody
      • Tonsillar lymphocyte LD78 beta protein antibody
      see all

    References

    ab193959 has not yet been referenced specifically in any publications.

    Publishing research using ab193959? Please let us know so that we can cite the reference in this datasheet.

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