Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      EWVQKYVSDLELSA
    • Amino acids
      80 to 93

Specifications

Our Abpromise guarantee covers the use of ab45686 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • 464.2
    • C C motif chemokine 3 like 1
    • CCL3L1
    • CCL3L3
    • Chemokine (C C motif) ligand 3 like 1
    • Chemokine (C C motif) ligand 3 like 3
    • Chemokine (C C motif) ligand 3 like, centromeric
    • chemokine (CC motif) ligand 3 like 1
    • CL3L1_HUMAN
    • D17S1718
    • G0/G1 switch regulatory protein 19-2
    • G0S19-2
    • LD78
    • LD78 beta(1-70)
    • LD78-beta(1-70)
    • LD78-beta(5-70)
    • LD78BETA
    • MGC104178
    • MGC12815
    • MGC182017
    • MIP1AP
    • PAT 464.2
    • SCYA3L
    • SCYA3L1
    • Small inducible cytokine A3 like 1 precursor
    • Small-inducible cytokine A3-like 1
    • Tonsillar lymphocyte LD78 beta
    • Tonsillar lymphocyte LD78 beta protein
    see all
  • Function
    Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab45686 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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