Anti-LDL (MDA oxidized) antibody [3G4] (ab63975)

Overview

  • Product name
    Anti-LDL (MDA oxidized) antibody [3G4]
    See all LDL (MDA oxidized) primary antibodies
  • Description
    Mouse monoclonal [3G4] to LDL (MDA oxidized)
  • Specificity
    Reacts with Low Density Lipoprotein (LDL) oxidised with Malonic dialdehyde (MDA). No crossreactions with LDL and other human plasma proteins were detected.
  • Tested applications
    Suitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human LDL (MDA oxidized)

  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab63975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Flow Cyt
  • Application notes
    Flow Cyt: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-oxidized LDL appear to be different from LDL oxidized by other means.
    • Cellular localization
      Secreted
    • Alternative names
      • Low density lipoprotein antibody
      • MDA oxidized LDL antibody
      • MDA oxidized low density lipoprotein antibody

    References for Anti-LDL (MDA oxidized) antibody [3G4] (ab63975)

    ab63975 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab63975.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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