Anti-LDL (MDA oxidized) antibody [3G4] (ab63975)

Overview

  • Product nameAnti-LDL (MDA oxidized) antibody [3G4]
    See all LDL (MDA oxidized) primary antibodies
  • Description
    Mouse monoclonal [3G4] to LDL (MDA oxidized)
  • SpecificityReacts with Low Density Lipoprotein (LDL) oxidised with Malonic dialdehyde (MDA). No crossreactions with LDL and other human plasma proteins were detected.
  • Tested applicationsSuitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified human LDL (MDA oxidized)

Properties

Applications

Our Abpromise guarantee covers the use of ab63975 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Flow Cyt
  • Application notesFlow Cyt: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceLow-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-oxidized LDL appear to be different from LDL oxidized by other means.
    • Cellular localizationSecreted
    • Alternative names
      • Low density lipoprotein antibody
      • MDA oxidized LDL antibody
      • MDA oxidized low density lipoprotein antibody

    References for Anti-LDL (MDA oxidized) antibody [3G4] (ab63975)

    ab63975 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"