Anti-LDL (MDA oxidized) antibody [4C7] (ab17354)

Overview

  • Product nameAnti-LDL (MDA oxidized) antibody [4C7]
    See all LDL (MDA oxidized) primary antibodies
  • Description
    Mouse monoclonal [4C7] to LDL (MDA oxidized)
  • SpecificityReacts with MDA-oxidized LDL but not with native LDL.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Low-density lipoprotein purified from human plasma and oxidized with malondialdehyde (MDA).

Properties

Applications

Our Abpromise guarantee covers the use of ab17354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    Immunoblotting: Use at an assay dependent dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceLow-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. MDA-oxidized LDL appear to be different from LDL oxidized by other means.
    • Cellular localizationSecreted
    • Alternative names
      • Low density lipoprotein antibody
      • MDA oxidized LDL antibody
      • MDA oxidized low density lipoprotein antibody

    References for Anti-LDL (MDA oxidized) antibody [4C7] (ab17354)

    ab17354 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for getting back to me and explaining these issues to me. I am convinced that there is a problem with this antibody in the system that you are using. I would like to offer you a credit note provided the antibody was purchased within the pa...

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    Thank you for your enquiry. I have been in touch with the source of this antibody and they have provided me with the following information. "I am afraid that only MDA (malon di aldehyde) oxidized LDL will work, as mentioned in the product speci...

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    Thank you for your enquiry. Yes, this antibody reacts with oxidized LDL but not with native LDL. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"