Overview

  • Product nameAnti-LEC antibody
    See all LEC primary antibodies
  • Description
    Rabbit polyclonal to LEC
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 9-58 (SLLVLILIIT SASRSQPKVP EWVNTPSTCC LKYYEKVLPR RLVVGYRKAL) of Human LEC (NP_004581).

  • Positive control
    • 721_B cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • Storage bufferConstituents: PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 14 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionShows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
  • Tissue specificityMainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-C motif chemokine 16 antibody
    • CCL16 antibody
    • CCL16_HUMAN antibody
    • Chemokine (C-C motif) ligand 16 antibody
    • Chemokine CC-4 antibody
    • Chemokine LEC antibody
    • CKb12 antibody
    • HCC-4 antibody
    • HCC4 antibody
    • IL-10-inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • ILINCK antibody
    • LCC-1 antibody
    • LCC1 antibody
    • Liver CC chemokine 1 precursor antibody
    • Liver expressed chemokine antibody
    • Liver-expressed chemokine antibody
    • LMC antibody
    • Lymphocyte and monocyte chemoattractant antibody
    • Monotactin 1 antibody
    • Monotactin-1 antibody
    • MTN-1 antibody
    • Mtn1 antibody
    • NCC-4 antibody
    • NCC4 antibody
    • New CC chemokine 4 antibody
    • SCYA16 antibody
    • SCYL4 antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 16 antibody
    • Small-inducible cytokine A16 antibody
    see all

Anti-LEC antibody images

  • Anti-LEC antibody (ab113220) at 1 µg/ml + 721_B cell lysate

    Predicted band size : 14 kDa

References for Anti-LEC antibody (ab113220)

ab113220 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"