Overview

  • Product name
    Anti-LEC antibody (Biotin)
    See all LEC primary antibodies
  • Description
    Goat polyclonal to LEC (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant full length human LEC protein.

Properties

  • Form
    Lyophilised:Centrifuge vial prior to opening. Reconstitute in 50 µl of sterile PBS containing 0.1% BSA to obtain a concentration of 1.0 mg/ml.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: 0.1% BSA, PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab83141 is sterile filtered. The antibody was purified by affinity chromatography and then biotinylated.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab83141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.25 - 1 µg/ml.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 14 kDa.

Target

  • Function
    Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
  • Tissue specificity
    Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-C motif chemokine 16 antibody
    • CCL16 antibody
    • CCL16_HUMAN antibody
    • Chemokine (C-C motif) ligand 16 antibody
    • Chemokine CC-4 antibody
    • Chemokine LEC antibody
    • CKb12 antibody
    • HCC-4 antibody
    • HCC4 antibody
    • IL-10-inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • ILINCK antibody
    • LCC-1 antibody
    • LCC1 antibody
    • Liver CC chemokine 1 precursor antibody
    • Liver expressed chemokine antibody
    • Liver-expressed chemokine antibody
    • LMC antibody
    • Lymphocyte and monocyte chemoattractant antibody
    • Monotactin 1 antibody
    • Monotactin-1 antibody
    • MTN-1 antibody
    • Mtn1 antibody
    • NCC-4 antibody
    • NCC4 antibody
    • New CC chemokine 4 antibody
    • SCYA16 antibody
    • SCYL4 antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 16 antibody
    • Small-inducible cytokine A16 antibody
    see all

References

ab83141 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab83141.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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