Recombinant
RabMAb

Anti-LEC antibody [EPR4451(2)] (ab126717)

Overview

  • Product name
    Anti-LEC antibody [EPR4451(2)]
    See all LEC primary antibodies
  • Description
    Rabbit monoclonal [EPR4451(2)] to LEC
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human LEC (O15467)

  • Positive control
    • Human LEC recombinant protein
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Dissociation constant (KD)
    KD = 2.00 x 10 -10 M
    Learn more about KD
  • Storage buffer
    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR4451(2)
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 14 kDa.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
    • Tissue specificity
      Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
    • Sequence similarities
      Belongs to the intercrine beta (chemokine CC) family.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • C-C motif chemokine 16 antibody
      • CCL16 antibody
      • CCL16_HUMAN antibody
      • Chemokine (C-C motif) ligand 16 antibody
      • Chemokine CC-4 antibody
      • Chemokine LEC antibody
      • CKb12 antibody
      • HCC-4 antibody
      • HCC4 antibody
      • IL-10-inducible chemokine antibody
      • IL10 inducible chemokine antibody
      • IL10 inducible chemokine antibody
      • ILINCK antibody
      • LCC-1 antibody
      • LCC1 antibody
      • Liver CC chemokine 1 precursor antibody
      • Liver expressed chemokine antibody
      • Liver-expressed chemokine antibody
      • LMC antibody
      • Lymphocyte and monocyte chemoattractant antibody
      • Monotactin 1 antibody
      • Monotactin-1 antibody
      • MTN-1 antibody
      • Mtn1 antibody
      • NCC-4 antibody
      • NCC4 antibody
      • New CC chemokine 4 antibody
      • SCYA16 antibody
      • SCYL4 antibody
      • Small inducible cytokine A16 precursor antibody
      • Small inducible cytokine A16 precursor antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 16 antibody
      • Small-inducible cytokine A16 antibody
      see all

    Images

    • Anti-LEC antibody [EPR4451(2)] (ab126717) at 1/1000 dilution + Human LEC recombinant protein at 0.01 µg

      Predicted band size : 14 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab126717 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab126717.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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