Anti-LEC antibody [MM0140-3J10] (ab89460)

Overview

  • Product name
    Anti-LEC antibody [MM0140-3J10]
    See all LEC primary antibodies
  • Description
    Mouse monoclonal [MM0140-3J10] to LEC
  • Tested applications
    Suitable for: WB, Neutralising, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant Human LEC.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    IgG fraction of culture supernatant purified by Protein G affinity chromatography and 0.2 µm filtered.
  • Clonality
    Monoclonal
  • Clone number
    MM0140-3J10
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab89460 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 14 kDa.
Neutralising Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • Function
    Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
  • Tissue specificity
    Mainly expressed in liver, also found in spleen and thymus. Highly expressed in LPS- and IFN-gamma-activated monocytes, weakly in some lymphocytes, including natural killer cells, gamma-delta T-cells, and some T-cell clones.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-C motif chemokine 16 antibody
    • CCL16 antibody
    • CCL16_HUMAN antibody
    • Chemokine (C-C motif) ligand 16 antibody
    • Chemokine CC-4 antibody
    • Chemokine LEC antibody
    • CKb12 antibody
    • HCC-4 antibody
    • HCC4 antibody
    • IL-10-inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • IL10 inducible chemokine antibody
    • ILINCK antibody
    • LCC-1 antibody
    • LCC1 antibody
    • Liver CC chemokine 1 precursor antibody
    • Liver expressed chemokine antibody
    • Liver-expressed chemokine antibody
    • LMC antibody
    • Lymphocyte and monocyte chemoattractant antibody
    • Monotactin 1 antibody
    • Monotactin-1 antibody
    • MTN-1 antibody
    • Mtn1 antibody
    • NCC-4 antibody
    • NCC4 antibody
    • New CC chemokine 4 antibody
    • SCYA16 antibody
    • SCYL4 antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine A16 precursor antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 16 antibody
    • Small-inducible cytokine A16 antibody
    see all

References for Anti-LEC antibody [MM0140-3J10] (ab89460)

ab89460 has not yet been referenced specifically in any publications.

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