Overview

  • Product nameAnti-LECT1 antibody
    See all LECT1 primary antibodies
  • Description
    Mouse polyclonal to LECT1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein (Human) LECT1 (NP_008946.1).

  • Positive control
    • LECT1 transfected 293T lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab68542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 39 kDa).

Target

  • FunctionBifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
  • Tissue specificityDetected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
  • Sequence similaritiesBelongs to the chondromodulin-1 family.
    Contains 1 BRICHOS domain.
  • Developmental stageExpressed at 9 weeks in developing cartilagenous bone rudiments.
  • Post-translational
    modifications
    After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
  • Cellular localizationEndomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
  • Information by UniProt
  • Database links
  • Alternative names
    • BRICD3 antibody
    • BRICHOS domain containing 3 antibody
    • CH-SP antibody
    • CHM I antibody
    • ChM-I antibody
    • CHM1 antibody
    • chondromodulin antibody
    • Chondromodulin I antibody
    • Chondromodulin-1 antibody
    • Chondromodulin-I antibody
    • Chondrosurfactant protein antibody
    • LECT 1 antibody
    • Lect1 antibody
    • LECT1_HUMAN antibody
    • Leukocyte cell derived chemotaxin 1 antibody
    • Multiple myeloma tumor suppressor 1 antibody
    • MYETS1 antibody
    see all

Anti-LECT1 antibody images

  • All lanes : Anti-LECT1 antibody (ab68542) at 1/500 dilution

    Lane 1 : LECT1 293T transfected cell lysate
    Lane 2 : non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L) at 1/5000 dilution

    Predicted band size : 39 kDa
    Observed band size : 43 kDa (why is the actual band size different from the predicted?)

References for Anti-LECT1 antibody (ab68542)

ab68542 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"