Overview

  • Product name
  • Description
    Rabbit polyclonal to LEFTY2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 25-351 of Human LEFTY2 (NP_003231).

  • Positive control
    • A431 whole cell lysate; HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab96564 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.

Target

  • Function
    Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.
  • Tissue specificity
    Mesenchymal cells of the endometrial stroma.
  • Involvement in disease
    Defects in LEFTY2 are the cause of left-right axis malformations (LRAM) [MIM:601877]. The defect includes left pulmonary isomerism, with cardiac anomalies characterized by complete atrioventricular canal defect and hypoplastic left ventricle, and interrupted inferior vena cava.
  • Sequence similarities
    Belongs to the TGF-beta family.
  • Developmental stage
    Transiently expressed before and during menstrual bleeding.
  • Post-translational
    modifications
    The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • EBAF antibody
    • Endometrial bleeding associated factor (left right determination factor A transforming growth factor beta superfamily) antibody
    • Endometrial bleeding associated factor antibody
    • Endometrial bleeding-associated factor antibody
    • Left right determination factor 2 antibody
    • Left right determination factor A antibody
    • Left-right determination factor 2 antibody
    • Left-right determination factor A antibody
    • LEFTA antibody
    • LEFTY 2 antibody
    • LEFTY2 antibody
    • LEFTYA antibody
    • LFTY2 transforming growth factor, beta -4 antibody
    • LFTY2, mouse, homolog of antibody
    • LFTY2_HUMAN antibody
    • MGC46222 antibody
    • Protein lefty 2 antibody
    • Protein lefty A antibody
    • Protein lefty-2 antibody
    • Protein lefty-A antibody
    • Protein lefty2 antibody
    • PSEC0024 antibody
    • TGF beta 4 antibody
    • TGF-beta-4 antibody
    • TGFB4 antibody
    • Transforming growth factor beta 4 antibody
    • Transforming growth factor beta-4 antibody
    see all

Images

  • Anti-LEFTY2 antibody (ab96564) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 41 kDa

References

ab96564 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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