Overview

  • Product nameAnti-LEPREL1 antibody
    See all LEPREL1 primary antibodies
  • Description
    Rabbit polyclonal to LEPREL1
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    internal sequence amino acids 307-447 of Human LEPREL1.

  • Positive control
    • Human skeletal muscle tissue. RT4 and U-251 MG cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • FunctionHas prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V.
  • Tissue specificityExpressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells.
  • Sequence similaritiesBelongs to the leprecan family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 4 TPR repeats.
  • Cellular localizationEndoplasmic reticulum. Golgi apparatus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4832416N06 antibody
    • AW553532 antibody
    • Leprecan like 1 antibody
    • Leprecan-like protein 1 antibody
    • Leprel1 antibody
    • MCVD antibody
    • MLAT4 antibody
    • Myxoid liposarcoma-associated protein 4 antibody
    • P3H2 antibody
    • P3H2_HUMAN antibody
    • Prolyl 3 hydroxylase 3 antibody
    • Prolyl 3-hydroxylase 2 antibody
    see all

Anti-LEPREL1 antibody images

  • ab121270 at 1/25 dilution staining LEPREL1 in paraffin-embedded Human skeletal muscle by Immunohistochemistry.
  • All lanes : Anti-LEPREL1 antibody (ab121270) at 1/250 dilution

    Lane 1 : Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11
    Lane 2 : RT-4 Cell lysate.
    Lane 3 : U-251 MG Cell lysate.
    Lane 4 : Human Plasma
    Lane 5 : Human Liver lysate.
    Lane 6 : Human Tonsil lysate.

    Developed using the ECL technique

References for Anti-LEPREL1 antibody (ab121270)

ab121270 has not yet been referenced specifically in any publications.

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