Overview

  • Product nameAnti-Leptin antibody
    See all Leptin primary antibodies
  • Description
    Rabbit polyclonal to Leptin
  • SpecificityThe antibody will recognize recombinant and native 16 kDa leptin from mouse. Reactivity with leptin from other sources is unknown.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant mouse leptin 16,000 MW produced in E. coli.

Properties

Applications

Our Abpromise guarantee covers the use of ab2095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA (suggested working dilution 1:2,400) and immunoblotting (suggested working dilution 1:200 to 1:400). Reactivity in other immunoassays is unknown. Optimal titers for other applications should be determined by the researcher.
  • Target

    • FunctionMay function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
    • Involvement in diseaseDefects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
    • Sequence similaritiesBelongs to the leptin family.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ94114 antibody
      • LEP antibody
      • LEP_HUMAN antibody
      • LEPD antibody
      • Leptin (murine obesity homolog) antibody
      • Leptin (obesity homolog, mouse) antibody
      • Leptin antibody
      • Leptin Murine Obesity Homolog antibody
      • Leptin Precursor Obesity Factor antibody
      • OB antibody
      • Obese protein antibody
      • Obese, mouse, homolog of antibody
      • Obesity antibody
      • Obesity factor antibody
      • Obesity homolog mouse antibody
      • Obesity Murine Homolog Leptin antibody
      • OBS antibody
      • OTTHUMP00000212285 antibody
      see all

    References for Anti-Leptin antibody (ab2095)

    This product has been referenced in:
    • Krishnapuram R  et al. Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab 300:E779-89 (2011). WB ; Mouse . Read more (PubMed: 21266671) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"