The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesFlow Cyt: 1/200.
FuncS: Use at an assay dependent dilution. Antibody inhibits CD2/CD58 interactions.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Use under non reducing conditions. Predicted molecular weight: 28 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionLigand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.