Anti-LGALS3BP antibody (ab217760)
Key features and details
- Rabbit polyclonal to LGALS3BP
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-LGALS3BP antibody
See all LGALS3BP primary antibodies -
Description
Rabbit polyclonal to LGALS3BP -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Synthetic peptide within Human LGALS3BP aa 300-400 conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q08380 -
Positive control
- Mouse serum lysate; Human colon carcinoma.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab217760 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/100 - 1/500.
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WB |
1/100 - 1/1000. Predicted molecular weight: 65 kDa.
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Notes |
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IHC-P
1/100 - 1/500. |
WB
1/100 - 1/1000. Predicted molecular weight: 65 kDa. |
Target
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Function
Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells. -
Tissue specificity
Ubiquitous. Detected in body fluids such as semen, milk, serum, tears, saliva and urine. Expressed by keratinocytes and fibroblasts. -
Sequence similarities
Contains 1 BACK (BTB/Kelch associated) domain.
Contains 1 BTB (POZ) domain.
Contains 1 SRCR domain. -
Cellular localization
Secreted. Secreted > extracellular space > extracellular matrix. - Information by UniProt
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Database links
- Entrez Gene: 3959 Human
- Entrez Gene: 19039 Mouse
- Entrez Gene: 245955 Rat
- Omim: 600626 Human
- SwissProt: Q08380 Human
- SwissProt: Q07797 Mouse
- SwissProt: O70513 Rat
- Unigene: 514535 Human
see all -
Alternative names
- 90K antibody
- 90K MAC 2 BP antibody
- Basement membrane autoantigen p105 antibody
see all
Images
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Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon carcinoma tissue labeling LGALS3BP
with ab217760 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.
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Anti-LGALS3BP antibody (ab217760) at 1/200 dilution + Mouse serum lysate
Secondary
Goat Anti-Rabbit IgG Antibody (H+L), HRP at 1/3000 dilution
Predicted band size: 65 kDa12% gel.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab217760 has been referenced in 2 publications.
- Jacquemin G et al. Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme. Elife 11:N/A (2022). PubMed: 35543624
- Anwaier G et al. Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5. Front Cell Dev Biol 9:697539 (2021). PubMed: 34262908