Overview

  • Product name
  • Description
    Rabbit polyclonal to Lgi3
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide, corresponding to a 12 amino acid peptide from near the center of Human Lgi3

  • Positive control
    • Human Kidney tissue and Human brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 62 kDa.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function
    May participate in the regulation of neuronal exocytosis.
  • Tissue specificity
    Widely expressed, with highest levels in brain and lung.
  • Sequence similarities
    Contains 7 EAR repeats.
    Contains 3 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Cellular localization
    Secreted. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle. Cell junction > synapse > synaptosome. Found in the synaptosomal membrane fraction.
  • Information by UniProt
  • Database links
  • Alternative names
    • Leucine rich repeat LGI family member 3 antibody
    • Leucine-rich glioma inactivated protein 3 antibody
    • Leucine-rich glioma-inactivated protein 3 antibody
    • Leucine-rich repeat LGI family member 3 antibody
    • LGI1 like protein 4 antibody
    • LGI1-like protein 4 antibody
    • LGI3 antibody
    • LGI3_HUMAN antibody
    • LGIL4 antibody
    see all

Images

  • Anti-Lgi3 antibody (ab113950) at 1 µg/ml + Human brain tissue lysate

    Predicted band size : 62 kDa
  • ab113950, at 5µg/ml dilution, staining Lgi3 in formalin-fixed, paraffin-embedded Human kidney tissue by Immunohistochemistry.

References

This product has been referenced in:
  • Park YH  et al. Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation. Invest Ophthalmol Vis Sci 57:508-26 (2016). Read more (PubMed: 26868754) »
  • Qian L  et al. Grb7 and Hax1 may colocalize partially to mitochondria in EGF-treated SKBR3 cells and their interaction can affect Caspase3 cleavage of Hax1. J Mol Recognit 29:318-33 (2016). WB ; Human . Read more (PubMed: 26869103) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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