Anti-Lhx4 antibody [LHX4E11E10] (ab50790)
Key features and details
- Mouse monoclonal [LHX4E11E10] to Lhx4
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
Overview
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Product name
Anti-Lhx4 antibody [LHX4E11E10]
See all Lhx4 primary antibodies -
Description
Mouse monoclonal [LHX4E11E10] to Lhx4 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Recombinant fragment -
Immunogen
Recombinant fragment corresponding to Human Lhx4 aa 50-200.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.0225% Potassium chloride, 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate, PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Ab50790 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (approximately 95%) fetal bovine serum. This antibody was filtered through a 0.22 µm membrane. -
Clonality
Monoclonal -
Clone number
LHX4E11E10 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab50790 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent dilution. Detects a band of approximately 34 kDa (predicted molecular weight: 43 kDa).
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Notes |
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WB
Use at an assay dependent dilution. Detects a band of approximately 34 kDa (predicted molecular weight: 43 kDa). |
Target
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Function
May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. -
Involvement in disease
Defects in LHX4 are the cause of pituitary hormone deficiency combined type 4 (CPHD4) [MIM:262700]; also known as short stature pituitary and cerebellar defects and small sella turcica. The disorder is characterized by short stature, pituitary and cerebellar defects, and small transverse depression crossing the midline on the superior surface of the body of the sphenoid bone which houses the pituitary gland.
Note=A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1;14)(q25;q32) with IGHG1. -
Sequence similarities
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains. -
Cellular localization
Nucleus. - Information by UniProt
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Alternative names
- CPHD4 antibody
- Gsh 4 antibody
- Gsh4 antibody
see all
Images
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Anti-Lhx4 antibody [LHX4E11E10] (ab50790) + Immunised recombinant protein.
Predicted band size: 43 kDa
Observed band size: 34 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab50790 has not yet been referenced specifically in any publications.