The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 3 µg/ml.
Use a concentration of 1 - 5 µg/ml.
FunctionCadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
Tissue specificityExpressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LI Cadherin antibody (ab54511)
LI Cadherin antibody (ab54511) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.
Western blot - LI Cadherin antibody (ab54511)
Western blot against tagged recombinant protein immunogen using ab54511 LI Cadherin antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Western blot - Anti-LI Cadherin antibody (ab54511)
Anti-LI Cadherin antibody (ab54511) at 1 µg/ml + Tissue lysate prepared from human intestine wall.
References for Anti-LI Cadherin antibody (ab54511)
This product has been referenced in:
Qiu HB et al. Targeting CDH17 suppresses tumor progression in gastric cancer by downregulating Wnt/ß-catenin signaling. PLoS One8:e56959 (2013).
Read more (PubMed: 23554857) »
Lee HJ et al. Gene expression profiling of metaplastic lineages identifies CDH17 as a prognostic marker in early stage gastric cancer. Gastroenterology139:213-25.e3 (2010).
Read more (PubMed: 20398667) »