Recombinant
RabMAb

Anti-LI Cadherin antibody [EPR3996] (ab109190)

Overview

  • Product name
    Anti-LI Cadherin antibody [EPR3996]
    See all LI Cadherin primary antibodies
  • Description
    Rabbit monoclonal [EPR3996] to LI Cadherin
  • Tested applications
    Suitable for: WB, IP, IHC-Pmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human LI Cadherin.

  • Positive control
    • Human small intestine, Human colon cancer, and HT-29 cell lysates, Human colon and Human colonic adenocarcinoma tissues
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Dissociation constant (KD)
    KD = 2.90 x 10 -12 M
    Learn more about KD
  • Storage buffer
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR3996
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab109190 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 120 kDa (predicted molecular weight: 92 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt or ICC.
  • Target

    • Function
      Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
    • Tissue specificity
      Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.
    • Sequence similarities
      Contains 7 cadherin domains.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • BILL-cadherin antibody
      • CAD17_HUMAN antibody
      • Cadherin 16 antibody
      • Cadherin 16, formerly antibody
      • Cadherin 17 antibody
      • cadherin 17, LI cadherin (liver-intestine) antibody
      • cadherin, liver-intestine antibody
      • Cadherin-17 antibody
      • CDH16 antibody
      • CDH16, formerly antibody
      • Cdh17 antibody
      • FLJ26931 antibody
      • Formerly Cadherin 16 antibody
      • Formerly CDH16 antibody
      • HPT 1 antibody
      • HPT-1 cadherin antibody
      • human intestinal peptide-associated transporter HPT-1 antibody
      • human peptide transporter 1 antibody
      • Intestinal peptide-associated transporter HPT 1 antibody
      • Intestinal peptide-associated transporter HPT-1 antibody
      • LI-cadherin antibody
      • Liver Cadherin antibody
      • liver intestine cadherin antibody
      • Liver-intestine cadherin antibody
      see all

    Images

    • All lanes : Anti-LI Cadherin antibody [EPR3996] (ab109190) at 1/1000 dilution

      Lane 1 : Human small intestine cell lysate
      Lane 2 : Human colon cancer cell lysate
      Lane 3 : HT-29 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 92 kDa
    • Immunohistochemical staining of paraffin-embedded Human colon tissue using ab109190 at a dilution of 1/250.
    • Immunohistochemical staining of paraffin-embedded Human colonic adenocarcinoma tissue using ab109190 at a dilution of 1/250.
    • ab109190 showing negative staining in Skeletal muscle tissue.

    • ab109190 showing negative staining in Normal kidney tissue.

    • ab109190 showing negative staining in Normal tonsil tissue.

    • ab109190 showing positive staining in Normal colon tissue.

    • ab109190 showing negative staining in Normal brain tissue.

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab109190 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab109190.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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