• Product nameAnti-LIGHT antibody
    See all LIGHT primary antibodies
  • Description
    Mouse monoclonal to LIGHT
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 61-170 of Human LIGHT



Our Abpromise guarantee covers the use of ab57901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
    • Tissue specificityPredominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
    • Sequence similaritiesBelongs to the tumor necrosis factor family.
    • Post-translational
      The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
    • Cellular localizationCytoplasm; Secreted and Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 258 antibody
      • CD258 antibody
      • CD258 antigen antibody
      • Delta transmembrane LIGHT antibody
      • Herpes virus entry mediator ligand antibody
      • Herpesvirus entry mediator A antibody
      • Herpesvirus entry mediator ligand antibody
      • herpesvirus entry mediator-ligand antibody
      • HVEM L antibody
      • HVEM-L antibody
      • HVEML antibody
      • Ligand for herpesvirus entry mediator antibody
      • LIGHT antibody
      • LTg antibody
      • soluble form antibody
      • TNF14 antibody
      • TNF14_HUMAN antibody
      • TNFSF 14 antibody
      • Tnfsf14 antibody
      • TNFSF14 protein antibody
      • TR 2 antibody
      • TR2 antibody
      • Tumor necrosis factor (ligand) superfamily, member 14 antibody
      • Tumor necrosis factor ligand superfamily member 14 antibody
      • Tumor necrosis factor ligand superfamily, member 14 antibody
      • Tumor necrosis factor receptor like 2 antibody
      • tumor necrosis factor receptor-like 2 antibody
      • Tumor necrosis factor superfamily member 14 antibody
      • Tumor necrosis factor superfamily member LIGHT antibody
      see all

    Anti-LIGHT antibody images

    • LIGHT antibody (ab57901) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human spleen.
    • Western blot against tagged recombinant protein immunogen using ab57901 LIGHT antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    References for Anti-LIGHT antibody (ab57901)

    ab57901 has not yet been referenced specifically in any publications.

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    I now have more information to share with you in regards to how the anti-LIGHT antibody (ab57901) was used in order to obtain the stainingpresented on the datasheet of this produc...

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