Overview

  • Product nameAnti-LIGHT antibody
    See all LIGHT primary antibodies
  • Description
    Rabbit polyclonal to LIGHT
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 191-240 (TSSSRVWWDS SFLGGVVHLE AGEKVVVRVL DERLVRLRDG TRSYFGAFMV) of Human LIGHT (NP_003798).

  • Positive control
    • 721_B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90133 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
  • Tissue specificityPredominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Post-translational
    modifications
    N-glycosylated.
    The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
  • Cellular localizationCytoplasm; Secreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 258 antibody
    • CD258 antibody
    • CD258 antigen antibody
    • Delta transmembrane LIGHT antibody
    • Herpes virus entry mediator ligand antibody
    • Herpesvirus entry mediator A antibody
    • Herpesvirus entry mediator ligand antibody
    • herpesvirus entry mediator-ligand antibody
    • HVEM L antibody
    • HVEM-L antibody
    • HVEML antibody
    • Ligand for herpesvirus entry mediator antibody
    • LIGHT antibody
    • LTg antibody
    • soluble form antibody
    • TNF14 antibody
    • TNF14_HUMAN antibody
    • TNFSF 14 antibody
    • Tnfsf14 antibody
    • TNFSF14 protein antibody
    • TR 2 antibody
    • TR2 antibody
    • Tumor necrosis factor (ligand) superfamily, member 14 antibody
    • Tumor necrosis factor ligand superfamily member 14 antibody
    • Tumor necrosis factor ligand superfamily, member 14 antibody
    • Tumor necrosis factor receptor like 2 antibody
    • tumor necrosis factor receptor-like 2 antibody
    • Tumor necrosis factor superfamily member 14 antibody
    • Tumor necrosis factor superfamily member LIGHT antibody
    see all

Anti-LIGHT antibody images

  • Anti-LIGHT antibody (ab90133) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 26 kDa

References for Anti-LIGHT antibody (ab90133)

ab90133 has not yet been referenced specifically in any publications.

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I am unfamiliar with the Ventana LIGHT product and was unable tro locate a reference to it on their website. We do however offer 5 antibodies against LIGHT. Three are Rabbit IgG polyclonals, the other two are prod...

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